Diagnosis unclear, infection source likely respiratory or urinary-tract

Mild to moderate infection

See UTI and acute bronchitis/community-acquired pneumonia  sections of guidance, choosing the first-line options for each infection. This will result in a combination of two or more antibiotics being prescribed.

Duration - refer to specific guidance

Review within 24 hours to confirm diagnosis, then follow appropriate infection specific recommendations

Severe infection

See hospital-acquired pneumonia as this combination will provide the same cover.

Duration 7-14 days

Review within 24 hours to confirm diagnosis, then follow appropriate infection specific recommendations

If sepsis has a cutaneous component or is arising from the skin

Refer to NECROTISING FASCIITIS

Review within 24 hours to confirm diagnosis, then follow appropriate infection specific recommendations