Influenza Treatment

Annual vaccination is essential for all those at risk of influenza. See Health Protection Scotland recommendations for Treatment and Prophylaxis of Influenza.  For otherwise healthy adults antivirals not recommended.

Treat ‘at risk’ patients, only when influenza is circulating in the community and ideally within 48 hours of onset  or in a care home where influenza is likely. At risk: 65 years or over, chronic respiratory disease (including COPD and asthma), significant cardiovascular disease (not hypertension), immunocompromised, diabetes mellitus, chronic neurological, renal or liver disease. Seek advice for  patients under 13 years and pregnant women.  Reduce dose in renal impairment (seek advice form Pharmacy)

For glossary of terms see Glossary

Drug details

Treatment of influenza

Oseltamivir 75mg twice daily

5 days

If resistance to Oseltamivir or severe immunosuppression

Zanamivir (inhaled) 10mg twice daily

5 days

Prophylaxis of influenza

Oseltamivir 75mg once daily

10 days

Prophylaxis of influenza if resistance to Oseltamivir

Zanamivir (inhaled) 10mg once daily

10 days

Last reviewed: 14 November 2017

Next review: 14 November 2019

Author(s): Antimicrobial Management Team

Approved By: TAM Subgroup of ADTC

Reviewer Name(s): Area Antimicrobial Pharmacist

Document Id: AMT152