Non-gonococcal urethritis

  • Cases of suspected NGU should be tested for Chlamydia, gonorrhoea and Mycoplasma Genitalium. 
  • It is recommended that patients with suspected NGU are referred to Sexual Health
  • Those with recurrent or persistent symptoms should be referred to Sexual Health.

Drug details

First episode. Test for C. trachomatis and M. genitalium

Doxycycline 100mg twice daily


7 days

OR Azithromycin 1g stat then 500mg once daily for 2 more doses

3 days (2g) in total

Levofloxacin should only be used if both doxycycline and azithromycin are not suitable.
Seek advice for recurrent or persistent infection.

OR Levofloxacin 500mg once daily

7 days

Last reviewed: 27 April 2022

Next review: 27 April 2025

Author(s): Antimicrobial Management Team

Approved By: TAM Subgroup of ADTC

Reviewer Name(s): Area Antimicrobial Pharmacist

Document Id: AMT127