Chlamydia Trachomatis/Urethritis

  • For complicate infection including PID and epididymo-orchitis, refer to sexual health.

  • Partner(s) will require testing +/- treatment

  • Refer to Sexual health for partner notification

Azithromycin is now second line due to rising resistance in Mycoplasma genitalium, a common co-infection with Chlamydia trachomatis. See BASHH Chlamydia Guidelines (update September 2018). 

See flowchart for Uncomplicated (asymptomatic) chlamydia for patients attending GP practices

Drug details

Chlamydia trachomatisuncomplicated (asymptomatic)

Doxycycline 100mg twice daily

7 days

 

Second line – see note above

OR Azithromycin 1g stat then 500mg once daily for 2 more doses

3 days (2g) in total

For rectal infections

Doxycycline 100mg twice daily

7 days

In pregnancy

Azithromycin 1g stat then 500mg once daily for 2 more doses

for 3 days (2g) in total

OR Erythromycin 500mg 4 times daily

7 days

OR Erythromycin 500mg twice daily

14 days

OR Amoxicillin  500mg 3 times daily

7 days

Last reviewed: 27 April 2022

Next review: 27 April 2025

Author(s): Antimicrobial Management Team

Approved By: TAM Subgroup of ADTC

Reviewer Name(s): Area Antimicrobial Pharmacist

Document Id: AMT124