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Important: Therapy notes

MHRA advice:
 Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations (January 2021) (

Important: Formulation and dosage details


Injection 20mg/2mL, 80mg/2mL


Follow local hospital guidelines, monitor drug levels, see:

  • gentamicin prescribing, administration and monitoring chart
  • gentamicin dose calculator
  • ‘Policy for use of intravenous gentamicin as part of the management of infective endocarditis in adults’
  • For surgical prophylaxis – see dosing table and give as a single dose (no monitoring).