Bowel cleansing preparations

Avoid bowel cleansing solutions as treatments for constipation. Use with caution in older or debilitated patients; check cautions and contra-indications before prescribing. Patients should stop iron preparations, antidiarrhoea preparations and, when possible, opiates 7 days before the procedure, commence a low residue diet 2 days before the procedure and take copious amounts of water or other clear fluids during treatment.

SODIUM PICOSULPHATE WITH MAGNESIUM CITRATE (First Line)

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Oral powder 10mg/sachet with magnesium citrate (s)

Dosage:

By mouth, 1 sachet in water in the morning before 8am and a second in the afternoon (2 to 4pm) on day preceding procedure.
See guidance - Oral Bowel Cleansing Agents

MACROGOL 3350 WITH POTASSIUM CHLORIDE, SODIUM BICARBONATE AND SODIUM CHLORIDE

Important: Therapy notes

Bowel cleansing before colonoscopy.
MHRA advice: Polyethylene glycol (PEG) laxatives and starch-based thickeners: potential interactive effect when mixed, leading to an increased risk of aspiration (April 2021) (www.gov.uk).

Important: Formulation and dosage details

Formulation:

Oral powder sachets 110 grams/sachet (VistaPrep®) (hospital use only)

Dosage:

3 to 4 litres, reconstituted solution taken over 4 hours, generally on the day of procedure; alternatively, it can be taken on the evening before procedure or started on the evening before procedure and completed on the morning of procedure.
See guidance - Oral Bowel Cleansing Agents